Bucks vs. Pacers Picks and Prediction – 4/22/2025

Milwaukee Bucks (49-33) vs. Indiana Pacers (47-35)
Time: 7:00 PM ET
Location: Gainbridge Fieldhouse, Indianapolis, IN
TV: NBA TV

Previous Game:

  • Pacers: Won Game 1, 117-98

  • Bucks: Snapped 8-game win streak with poor shooting night

Head-to-Head:

Indiana now leads the series 1-0 after dominating Game 1 at home. The Bucks struggled from deep (9-for-37), but Giannis still dropped 36 points and 12 rebounds. Despite the loss, Milwaukee holds a 3-2 edge in the last five head-to-head matchups.

Milwaukee Bucks Breakdown:

Milwaukee closed the regular season red-hot and had been averaging 122.4 points per game over their last 10. In Game 1, Giannis was elite, but the rest of the starters combined for just 14 points. With Damian Lillard questionable, the Bucks need stronger contributions from role players like Bobby Portis and Khris Middleton. Milwaukee is still 4-1 ATS in their last 5 games, and they won 8 of their final 9 regular season games.

Key Players:

  • Giannis Antetokounmpo: 25.8 PPG, 9.3 RPG, 7.7 APG

  • Khris Middleton: 15.1 PPG, 5.3 APG

Indiana Pacers Breakdown:

Indiana continues to be lethal at home, going 29-11 in the regular season and 8-2 in their last 10. In Game 1, they shot 52% from the field and dished out 28 assists, showcasing their team chemistry. Tyrese Haliburton was quiet scoring-wise, but Pascal Siakam and the Pacers' supporting cast stepped up big. Still, Indiana’s defense is average, and they could be exposed if Milwaukee regains their shooting form.

Key Players:

  • Tyrese Haliburton: 13.9 PPG, 7.7 APG

  • Pascal Siakam: 4.8 RPG, strong post presence

Betting Trends:

Milwaukee Bucks:

  • 4-1 ATS in last 5 games

  • OVER in 9 of last 12 games

  • 8-1 SU in last 9 games

Indiana Pacers:

  • 8-1 SU in last 9 games

  • OVER in 8 of last 12 overall

  • OVER in 14 of last 20 vs. Milwaukee

Exact Score Prediction:

Milwaukee Bucks 115 – Indiana Pacers 111

Our Best Bet:

Milwaukee Bucks +4.5 (-110)

Milwaukee is in a perfect bounce-back spot. They’ve been red-hot overall, and Game 1’s poor shooting performance (especially from three) was more of an outlier than a trend. Giannis looked unstoppable, and if even one other starter steps up offensively, this game is well within reach—or even theirs to take outright. Indiana will struggle to replicate their 52% shooting, and Milwaukee’s playoff adjustments should help them cover the spread, if not win outright.

Want access to our premium picks? Click here for a FREE 1 day trial

Back to blog